From October 26th to 29th, the SMART Symposium on AI-Driven Computational Biology and Medicine, organized by Shenzhen Medical Academy of Research and Translation (SMART) and Shenzhen Bay Laboratory (SZBL), was grandly held at the Shenzhen Guangming Cloud Park International Conference Center. This symposium brought together top experts and scholars in the field of biomedicine to deeply discuss cutting-edge topics such as computational biology, drug design, artificial intelligence, and structural prediction, aiming to promote the development of intelligent biology and medicine-related fields. The organizing committee of the conference, composed of renowned scholars such as Jiali Gao, Yaoqi Zhou, and Qin Peng, will share the latest research findings with participants and engage in in-depth discussions on the future trends in the field of intelligent biology and medicine.