On May 28th, Shenzhen Bay Laboratory held an academic exchange series of Happy Hour (Phase 9) activities. Dr. Yaoqi Zhou invited Dr. Yang Yu , an investigator from the Institute of Biophysics, Chinese Academy of Sciences, to make a special sharing: Eukaryotic CRISPR: a piRNA-guided “innate immune” system in Genome defence; more than 30 people from the research institute/center online/offline participated in the activity.